Mouse anti-Factor VIII, Clone: RFF-VIIIC/10, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP1410210.1MG
DescriptionFactor VIII Monoclonal antibody specifically detects Factor VIII in Human samples. It is validated for Western Blot, ELISA, Radioimmunoassay.
|PBS (pH 7.4) with 0.09% Sodium Azide|
|Affinity purified human Factor VIII|
|Protein G purified|
|ELISA, Radioimmune Assays, Western Blot|
|Western Blot 1:100, ELISA 1:100-1:2000, Radioimmunoassay 1:100-1:2000|
|AHF, Antihemophilic factor, coagulation factor VIII, procoagulant component, coagulation factor VIIIc, DXS1253E, F8Ccoagulation factor VIII, factor VIII F8B, FVIII, HEMAF8B, Procoagulant component|
|Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.|
|This antibody recognises human Factor VIII, an essential blood coagulation factor. Whilst circulating in the blood, it is mostly stably complexed to von Willebrand factor. It is activated through cleavage at various sites, dissociates from the complex and interacts with Factor IXa, in the presence of calcium ions and phospholipids, to convert Factor X to the activated Factor Xa, which activates thrombin. Thrombin cleaves fibrinogen into fibrin, which polymerises and cross-links to form a blood clot. The activated Factor VIII is proteolytically inactivated and cleared from the bloodstream. Clone RFF-VIIIC/10 recognises an epitope within the non-functional, middle domain of full-length Factor VIII.|
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