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Mouse anti-Fascin, Clone: FSCN1/417, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen Fascin
Clone FSCN1/417
Concentration 0.2mg/mL
Immunogen Full length recombinant human FSCN1 protein
Gene ID (Entrez) 6624
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24438301 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2443830.1MG
0.1 mg Each for $299.00
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NBP24438300 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2443830.02MG
0.02 mg Each for $129.00
Add to cart
 
NBP24438302 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2443830.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Fascin Monoclonal antibody specifically detects Fascin in Human samples. It is validated for Western Blot, Simple Western, Flow Cytometry, Immunohistochemistry-Paraffin, SDS-Page, Immunofluorescence.
Specifications

Specifications

Fascin
0.2mg/mL
6624
Monoclonal
Mouse
IgG2a Kappa
Purified
RUO
Protein A or G purified
FSCN1/417
Full length recombinant human FSCN1 protein
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
Recognizes a protein of 55kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin's disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
Unconjugated
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Store at 4C.

For Research Use Only

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