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Mouse anti-Fc gamma RIIIA/CD16a, Clone: HuNK2, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2448360.1MG

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Catalog No. NBP24483601


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

Fc gamma RIIIA/CD16a Monoclonal antibody specifically detects Fc gamma RIIIA/CD16a in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.
Specifications

Specifications

Fc gamma RIIIA/CD16a
HuNK2
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
FCGR3A
Human peripheral blood lymphocytes from a NK-leukemia patient.
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes a protein of 50-65kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
Flow Cytometry, SDS-Page, Immunofluorescence
0.2 mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
P08637
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
Mouse
IgG2a Kappa
0.1 mg
Astrocyte Markers, Cellular Markers, Cytokine Research, Cytoskeleton Markers, Growth and Development, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Primary
2214
Human
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