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fMLP Receptor Mouse anti-Human, Alexa Fluor 647, Clone: 5F1, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565623

Catalog No. BDB565623


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Description

Description

The 5F1 monoclonal antibody specifically binds to the N-formyl-leucyl-phenylalanine receptor (fMLP receptor), which is also known as, Formyl peptide receptor 1 (FPR1). This 55-70 kDa receptor is expressed on neutrophils, monocytes, macrophages, and liver parenchymal cells. It is composed of seven hydrophobic membrane spanning regions and is a member of the rhodopsin superfamily of G protein-coupled receptors. N-formyl peptides interact with fMLP receptors and induce neutrophil chemotaxis, phagocytosis, production of superoxide radicals and release of proteolytic enzymes. The binding of the 5F1 antibody to the fMLP receptor can be blocked by fMLP peptide.

Specifications

Specifications

fMLP Receptor
5F1
fMet-Leu-Phe receptor; formyl peptide receptor 1; FPR1; FPR
Affinity Purified
Human fMLP receptor Transfected Cell Line
Affinity Chromatography
RUO
Primary
Human
Flow Cytometry
Alexa Fluor 647
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Murine
IgG1, κ
100 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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