Learn More
CD25 Mouse anti-Human, Brilliant Violet 711, Clone: M-A251, BD Optibuild™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 740776
Description
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as low-affinity interleukin-2 receptor alpha chain subunit (IL-2R α ). CD25 is expressed on regulatory T cells, activated lymphocytes (T and B), and monocytes. It associates with the IL-2R β /CD122 and IL-2R γ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2R α is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
Specifications
CD25 | |
Monoclonal | |
0.2mg/mL | |
IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55 | |
Mouse | |
50 μg | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
Flow Cytometry | |
M-A251 | |
Brilliant Violet 711 | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
For Research Use Only