CD25 Mouse anti-Human, Brilliant Violet 711, Clone: M-A251, BD Optibuild™
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 740776
The M-A251 monoclonal antibody specifically binds to the 55 kDa type I transmembrane glycoprotein known as low-affinity interleukin-2 receptor alpha chain subunit (IL-2R α ). CD25 is expressed on regulatory T cells, activated lymphocytes (T and B), and monocytes. It associates with the IL-2R β /CD122 and IL-2R γ/CD132 receptor chains to form the high-affinity IL-2R complex. CD25 expression on T and B lymphocytes is upregulated by antigenic or mitogenic stimulation. Soluble CD25/IL-2R α is produced as a consequence of lymphocyte stimulation and is found in biological fluids following inflammatory responses.
|Brilliant Violet 711|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
|IL-2R; IL2RA; IL-2Rα; TCGFR; TAC antigen; p55|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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