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Mouse anti-ICAM-1/CD54, Clone: F4-31C2, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2443320.02MG

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Catalog No. NBP24433200


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

ICAM-1/CD54 Monoclonal antibody specifically detects ICAM-1/CD54 in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.
Specifications

Specifications

ICAM-1/CD54
F4-31C2
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
BB2, CD54, CD54 antigen, cell surface glycoprotein P3.58, human rhinovirus receptor, ICAM-1, intercellular adhesion molecule 1, intercellular adhesion molecule 1 (CD54), human rhinovirus receptor, Major group rhinovirus receptor, P3.58
Mouse
IgG2a Kappa
0.02 mg
Adaptive Immunity, Cancer, Cell Biology, Immunology, Mesenchymal Stem Cell Markers, Stem Cell Markers
Primary
3383
Human
Flow Cytometry, SDS-Page, Immunofluorescence
0.2 mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Purified
ICAM1
Human umbilical cord vein endothelial cells (HUVEC)
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes an 85-115kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1). This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.
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