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Mouse anti-Insulin, Clone: SPM531, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2347800.1 MG

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Catalog No. NBP23478001


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Description

Description

Insulin Monoclonal antibody specifically detects Insulin in Human, Rat, Porcine, Bovine, Rabbit samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.
Specifications

Specifications

Insulin
SPM531
Unconjugated
10mM PBS - BSA free with No Preservative
Purified
INS
Full length (1-84 amino acid) purified pig insulin, conjugated to KLH
6 kDa
0.1 mg
Diabetes Research, Immune System Diseases, Immunology, Stem Cell Markers
Primary
3630
Protein A purified
ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
1.0 mg/mL
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
P01308
IDDM2, ILPR, insulin, IRDN, MODY10, proinsulin
Mouse
IgG1 Kappa
Protein A purified
RUO
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Monoclonal
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Bovine, Human, Porcine, Rabbit, Rat
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