Mouse anti-Integrin beta 3/CD61, Clone: 25E11., Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2449640.2MG

Catalog No. NBP24496402

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

Integrin beta 3/CD61 Monoclonal antibody specifically detects Integrin beta 3/CD61 in Human samples. It is validated for Flow Cytometry, Immunofluorescence.

Specifications

• Antigen: Integrin beta 3/CD61
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml
• Gene Accession No.: P05106
• Gene Symbols: ITGB3
• Immunogen: Normal blood mononuclear cells activated by mixed lymphocyte reaction
• Quantity: 0.2 mg
• Research Discipline: Cancer, Cytoskeleton Markers, Signal Transduction
• Gene ID (Entrez): 3690
• Target Species: Human
• Form: Purified

• Applications: Flow Cytometry, Immunofluorescence
• Clone: 25E11.
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: CD61, CD61 antigen, GP3Aplatelet glycoprotein IIIa, GPIIIaintegrin beta-3, integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61), ITG B3, Platelet membrane glycoprotein IIIa
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). The protein detectable is a complex of CD41 and CD61.The apparent molecular weight of the GPIIIa by SDS-PAGE is 105kDa reduced and 90kDa unreduced. Ligands are fibronectin, fibrinogen, von Willebrand factor, vitronectin and thrombospondin. Residues 237-248 of GPIIIa or CD61 are critical in adhesive protein binding
• Content And Storage: Store at 4C.
• Isotype: IgM κ

For Research Use Only