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Melan-A/MART-1 Antibody (M2-7C10), Novus Biologicals™
Mouse Monoclonal Antibody has been used in 8 publications
Supplier: Novus Biologicals NBP2151970.2MG
Description
Melan-A/MART-1 Monoclonal specifically detects Melan-A/MART-1 in Human, Equine, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.Specifications
Melan-A/MART-1 | |
Monoclonal | |
0.2mg/mL | |
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, SDS-Page | |
Q16655 | |
MLANA | |
Recombinant human Melan-A protein was used as immunogen to generate the Melan-A antibody. | |
0.2 mg | |
Cytoskeleton Markers, Immunology | |
2315 | |
Human, Mouse (Negative), Rat (Negative) | |
Purified |
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin) | |
M2-7C10 | |
Unconjugated | |
PBS with 0.05% BSA. with 0.05% Sodium Azide | |
Antigen LB39-AA, Antigen SK29-AA, Mart 1 Melan A, MART1MART-1, melan-A, melanoma antigen recognized by T-cells 1, Protein Melan-A | |
Mouse | |
Protein G purified | |
RUO | |
Primary | |
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. | |
Store at 4C. | |
IgG2b κ |
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