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Mouse anti-MS4A1/CD20, Clone: 93-1B3, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2447480.02MG

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Catalog No. NBP24474800


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

CD20 Monoclonal antibody specifically detects CD20 in Human samples. It is validated for Flow Cytometry, Immunofluorescence.
Specifications

Specifications

CD20
93-1B3
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
B1, B-lymphocyte antigen CD20, B-lymphocyte cell-surface antigen B1, B-lymphocyte surface antigen B1, Bp35MGC3969, CD20 antigen, CD20 receptor, CD20S7, CVID5, LEU-16, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, membrane-spanning 4-domains, subfamily A, member 1, MS4A2
Mouse
IgG1 Kappa
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes a protein of 30-33kDa, which is identified as CD20 (Workshop V; Code CD20.4). It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.
Flow Cytometry, SDS-Page, Immunofluorescence
0.2 mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Purified
MS4A1
Stimulated human leukocytes
35 kDa
0.02 mg
Adaptive Immunity, Cancer Stem Cells, Cell Biology, Cytokine Research, Immunology, Signal Transduction, Stem Cell Markers, Tumor Biomarkers
Primary
931
Human
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