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Mouse anti-MUC-1, Clone: 139H2, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen MUC-1
Clone 139H2
Concentration 0.2mg/mL
Immunogen Human milk-fat globule membranes (HMFGM)
Gene ID (Entrez) 4582
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Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24466600 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2446660.02MG
0.02 mg Each for $129.00
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NBP24466601 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2446660.1MG
0.1 mg Each for $299.00
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NBP24466602 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2446660.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

MUC1 Monoclonal antibody specifically detects MUC1 in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

MUC-1
0.2mg/mL
4582
Monoclonal
Mouse
IgG1 Kappa
Purified
RUO
Protein A or G purified
139H2
Human milk-fat globule membranes (HMFGM)
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
This MAb reacts with MUC1. The dominant epitope of this MAb has not yet been determined. MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and over expressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four c-erbB receptors and localize with c-erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.
Unconjugated
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Store at 4C.

For Research Use Only

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