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NF-H Antibody (NE14), Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2447280.1MG
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin)
NF-H Monoclonal specifically detects NF-H in Human, Mouse, Rat, Porcine, Bovine, Chicken, Feline, Guinea Pig, Gerbil, Rabbit samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.Specifications
NF-H | |
Monoclonal | |
0.2mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.25 - 0.5 ug/ml, SDS-Page | |
P12036 | |
NEFH | |
Crude neurofilament preparation from porcine spinal cord | |
Protein A or G purified | |
RUO | |
Primary | |
This MAb reacts with a 200kDa protein, identified as heavy sub-unit of neurofilaments (NF-H). It reacts specifically with the phosphorylated KSP/KEP segment at the C-terminus of the heavy subunit (NF-H) of neurofilaments. After dephosphorylation of neurofilaments with alkaline phosphatase, this Ab no longer binds. Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also expr | |
Store at 4C. | |
IgG1 |
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page | |
NE14 | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
200 kDa neurofilament protein, KIAA0845, Neurofilament Heavy (200kDa), neurofilament heavy polypeptide, Neurofilament triplet H protein, neurofilament, heavy polypeptide, neurofilament, heavy polypeptide 200kDa, NF200, NFH, NF-H | |
Mouse | |
200 kDa | |
0.1 mg | |
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience | |
4744 | |
Human, Mouse, Rat, Porcine, Chicken, Feline, Gerbil, Guinea Pig, Primate, Rabbit | |
Purified |
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