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Mouse anti-p21/CIP1/CDKN1A, Clone: SPM306, Novus Biologicals™

Mouse Monoclonal Antibody

$129.00 - $299.00

Specifications

Antigen p21/CIP1/CDKN1A
Clone SPM306
Concentration 0.2mg/mL
Immunogen Human recombinant p21 protein
Gene ID (Entrez) 1026
View More Specs

Products 3
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP24452600 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2445260.02MG
0.02 mg Each for $129.00
Add to cart
 
NBP24452601 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2445260.1MG
0.1 mg Each for $299.00
Add to cart
 
NBP24452602 View Documents Novus BiologicalsSupplier Diversity Partner
NBP2445260.2MG
0.2 mg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

p21/CIP1/CDKN1A Monoclonal antibody specifically detects p21/CIP1/CDKN1A in Human, Mouse (Negative), Rat (Negative) samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

p21/CIP1/CDKN1A
0.2mg/mL
1026
Monoclonal
Mouse
IgG2a Kappa
Purified
RUO
Protein A or G purified
SPM306
Human recombinant p21 protein
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Primary
This MAb recognizes a 21kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk s and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
Unconjugated
Western Blot, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Store at 4C.

For Research Use Only

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