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Mouse anti-p27/Kip1, Clone: SX53G8, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

$366.50

Specifications

Antigen p27/Kip1
Clone SX53G8
Concentration 1.0 mg/mL
Immunogen Purified GST-p27 fusion protein of human origin
Gene Accession No. P46527
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP23471801
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Novus Biologicals
NBP2347180.1 MG
0.1 mg
Each for $366.50
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NBP23471802
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Novus Biologicals
NBP2347180.2 MG
0.2 mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

p27/Kip1 Monoclonal antibody specifically detects p27/Kip1 in Human, Mouse, Rat, Primate samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.
Specifications

Specifications

p27/Kip1
1.0 mg/mL
P46527
10mM PBS - BSA free with No Preservative
This MAb recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. In Western blotting of cell lysates from 7 human breast cancer cell lines (ZR75-1, ZR75-30, MCF-7, MDAMB453, T47D, CAL51, 734B), the antibody labels a single band corresponding to p27Kip1. It functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. Reportedly, low p27 expression has been associated with unfavorable prognosis in renal cell carcinoma, colon carcinoma, breast carcinomas, non-small-cell lung carcinoma, hepatocellular carcinoma, multiple myeloma, and lymph node metastases in papillary carcinoma of the thyroid, as well as a more aggressive phenotype in carcinoma of the cervix.
Primary
Mouse
Unconjugated
Protein A purified
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
SX53G8
Purified GST-p27 fusion protein of human origin
1027
Protein A purified
Monoclonal
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG1 Kappa
Purified
RUO
SDS
Product Certifications

For Research Use Only

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