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Mouse anti-p53, Clone: SPM590, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

$421.50

Specifications

Antigen p53
Clone SPM590
Concentration 1.0 mg/mL
Immunogen Recombinant human wild type p53 protein expressed in E. coli.
Gene Accession No. P04637
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
NBP23443401
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Novus Biologicals
NBP2344340.1 MG
0.1 mg
Each for $421.50
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NBP23443402
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Novus Biologicals
NBP2344340.2 MG
0.2 mg This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

p53 Monoclonal antibody specifically detects p53 in Human, Bovine, Primate samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready.
Specifications

Specifications

p53
1.0 mg/mL
P04637
10mM PBS - BSA free with No Preservative
Recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.
Primary
Mouse
Unconjugated
Protein A purified
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
SPM590
Recombinant human wild type p53 protein expressed in E. coli.
7157
Protein A purified
Monoclonal
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG2b Kappa
Purified
RUO
SDS
Product Certifications

For Research Use Only

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