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Mouse anti-PD-1, Clone: SPM597, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2443990.02MG

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Catalog No. NBP24439900


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

PD-1 Monoclonal antibody specifically detects PD-1 in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
Specifications

Specifications

PD-1
SPM597
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
PDCD1
Recombinant full-length human PDCD1 protein
55 kDa
0.02 mg
Apoptosis, Stem Cell Markers
Primary
5133
Human
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
0.2mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Q15116
CD279, CD279 antigen, hPD-1, PD1hPD-l, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2
Mouse
IgG1 Kappa
Protein A or G purified
RUO
Store at 4C.
Monoclonal
PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
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