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Mouse anti-TAG-72, Clone: CC49, Azide Free, Novus Biologicals™

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2331280.2MG

Catalog No. NBP23312802

This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Specifications

Specifications

TAG-72
CC49
Unconjugated
10mM PBS - BSA free with No Preservative
CA 72-4, Protein TAG-72, tag 72, tag-72 Protein TAG-72
Purified TAG-72 protein
220 kDa
0.2 mg
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Monoclonal
Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
Human, Rat, Bovine, Canine
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
1.0 mg/mL
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
Purified
Mouse
IgG1 Kappa
Protein A purified
RUO
Primary
182875
Protein A purified
Documents
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