Mouse anti-TAG-72, Clone: CC49, Novus Biologicals™

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
NBP2313832	Novus Biologicals NBP2313830.02MG	0.02 mg
NBP23138301	Novus Biologicals NBP2313830.1MG	0.1 mg
NBP23138302	Novus Biologicals NBP2313830.2MG	0.2 mg

Description

TAG-72 Monoclonal antibody specifically detects TAG-72 in Human, Rat, Bovine, Canine samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Specifications

• Antigen: TAG-72
• Concentration: 0.2mg/mL
• Gene ID (Entrez): 182875
• Reconstitution: Protein A purified
• Monoclonal or Polyclonal: Monoclonal
• Storage Requirements: Store at 4C.
• Isotype: IgG1 Kappa
• Format: Purified
• Regulatory Status: RUO

• Clone: CC49
• Immunogen: Purified TAG-72 protein
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Test Specificity: Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG-72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.
• Primary or Secondary: Primary
• Host Species: Mouse
• Conjugate: Unconjugated
• Purification Method: Protein A purified
• Applications: Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

For Research Use Only