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TLR5 Mouse anti-Mouse, PE, Clone: ACT5, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565645

Catalog No. BDB565645


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Description

Description

The ACT5 monoclonal antibody specifically binds to the mouse Toll-like receptor 5 (TLR5), which is also known as CD285. TLR5 is a type I transmembrane glycoprotein and a member of the Toll-like receptor (TLR) family. It is expressed on the surface of monocytes, dendritic cells, neutrophils, and mucosal epithelial cells. TLR5 is a pattern recognition receptor that binds to bacterial flagellin. TLR5 signaling leads to the activation of cells that produce proinflammatory cytokines and chemokines, such as IL-6 and MCP-1. TLR5 thus plays a major role in initiating innate and adaptive immune responses.

Specifications

Specifications

TLR5
ACT5
PE
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG1, κ
0.1mg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
TLR5; CD285; Tlr5; Toll-like receptor 5
Affinity Purified
Mouse TLR5 Transfected Cell Line
Affinity Chromatography
RUO
Primary
Murine
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