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Mouse anti-TOP1MT, Clone: TOP1MT/488, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2443600.1MG

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Catalog No. NBP24436001


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

TOP1MT Monoclonal antibody specifically detects TOP1MT in Human samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, SDS-Page, Flow (Intracellular), Immunofluorescence.
Specifications

Specifications

TOP1MT
TOP1MT/488
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
TOP1MT
Recombinant full-length human TOP1MT protein
70 kDa
0.1 mg
Store at 4C.
Monoclonal
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
0.2mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Q969P6
mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial
Mouse
IgG2b Kappa
Protein A or G purified
RUO
Primary
116447
Human
Documents
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