TRIM29 Antibody (TRIM29/1042), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2444040.2MG

Catalog No. NBP24440402

Description

Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunofluorescence

TRIM29 Monoclonal antibody specifically detects TRIM29 in Human samples. It is validated for Western Blot, Flow Cytometry, SDS-Page, Immunofluorescence.

Specifications

• Antigen: TRIM29
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Dilution: Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
• Gene Accession No.: Q14134
• Gene Symbols: TRIM29
• Immunogen: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Gene ID (Entrez): 23650
• Target Species: Human
• Form: Purified

• Applications: Western Blot, Flow Cytometry, SDS-Page, Immunofluorescence
• Clone: TRIM29/1042
• Conjugate: Unconjugated
• Formulation: 1.0mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Alias: Ataxia telangiectasia group D-associated protein, ATDCataxia-telangiectasia group D-associated protein, FLJ36085, tripartite motif containing 29, tripartite motif protein TRIM29, tripartite motif-containing 29, tripartite motif-containing protein 29
• Host Species: Mouse
• Molecular Weight of Antigen: 66 kDa
• Quantity: 0.2 mg
• Primary or Secondary: Primary
• Test Specificity: It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ∼90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
• Content And Storage: Store at 4C.
• Isotype: IgG2b κ

For Research Use Only