MilliporeSigma™ Mouse anti-Trpv4, Clone: 1B2.6,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABS466

Catalog No. MABS466MI

Description

Specifically detects Trpv4 clone: 1B2.6 in Human, Mouse samples, and it is validated for Immunocytochemistry, Western Blotting

Transient receptor potential cation channel subfamily V member 4 is a multitransmembrane non-selective cation channel encoded by the TRPV4 (also known as CMT2C, HMSN2C, OTRPC4, SMAL, SPSMA, SSQTL1, TRP12, VR-OAC, VRL-2, VRL2, VROAC) gene and belong to the OSM9-like transient receptor potential channel (OTRPC) subfamily within the transient receptor potential (TRP)3 superfamily of channels. Ankyrin (ANK) repeats/domains are shown to be important for functional channel expression, and ANK domain mutations are found in patients suffering from Spinal muscular atrophies (SMA, also known as hereditary motor neuropathies) and hereditary motor and sensory neuropathies (HMSN). (PMID 16293632, 20037587, 20037588).

Specifications

• Antigen: Trpv4
• Classification: Monoclonal
• Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: VRL2; VROAC; TRPV4
• Immunogen: GST-tagged recombinant protein corresponding to human Trpv4.
• Quantity: 100 μg
• Research Discipline: Signaling
• Gene ID (Entrez): NP_001170899
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG2a κ

• Applications: Immunocytochemistry, Western Blot
• Clone: 1B2.6
• Gene Accession No.: Q9HBA0
• Host Species: Mouse
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Purified

For Research Use Only