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Mouse anti-TYRP1, Clone: TA99 + TYRP1/807, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2446220.02MG

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Catalog No. NBP24462200

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Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence

TYRP1 Monoclonal antibody specifically detects TYRP1 in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry-Frozen, Immunofluorescence.


TA99 + TYRP1/807
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP
Protein A or G purified
Human, Mouse
Western Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence
0.2 mg/mL
Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
SK-MEL-23 cells (TA99); Recombinant full-length human TYRP1 protein (TYRP1/807)
75 kDa
0.02 mg
Store at 4C.
It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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