Mouse anti-TYRP1, Clone: TA99 + TYRP1/807, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2446220.1MG
Ensure accurate, reproducible results in Western Blot, Flow Cytometry, Immunohistochemistry (Frozen), ImmunofluorescenceTYRP1 Monoclonal antibody specifically detects TYRP1 in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry-Frozen, Immunofluorescence.
|TA99 + TYRP1/807|
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 126.96.36.199, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP|
|Protein A or G purified|
|Western Blot, Flow Cytometry, Immunohistochemistry (Frozen), Immunofluorescence|
|Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Frozen 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml|
|SK-MEL-23 cells (TA99); Recombinant full-length human TYRP1 protein (TYRP1/807)|
|Store at 4C.|
|It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.|
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