Mouse anti-TYRP1, Clone: TYRP1/807, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2446210.1MG
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), ImmunofluorescenceTYRP1 Monoclonal antibody specifically detects TYRP1 in Human, Mouse samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 220.127.116.11, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP|
|Protein A or G purified|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence|
|Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml|
|Recombinant full-length human TYRP1 protein|
|Store at 4C.|
|It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.|
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