Mouse anti-UACA, Clone: UACA/1222, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2443570.02MG
Ensure accurate, reproducible results in Western Blot, Flow Cytometry, ImmunofluorescenceUACA Monoclonal antibody specifically detects UACA in Human, Mouse samples. It is validated for Western Blot, Flow Cytometry, Immunofluorescence.
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|FLJ10128, KIAA1561MGC141969, MGC141967, nuclear membrane binding protein, NUCLING, uveal autoantigen with coiled coil domains and ankyrin repeats, uveal autoantigen with coiled-coil domains and ankyrin repeats|
|Protein A or G purified|
|Store at 4C.|
|UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.|
|Western Blot, Flow Cytometry, Immunofluorescence|
|Western Blot 0.5 - 1.0 ug/ml, Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence 0.5 - 1.0 ug/ml|
|Recombinant human UACA protein|
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