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Mouse anti-VCAM-1/CD106, Clone: B-K9, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP2446160.1MG

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Catalog No. NBP24461601


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Description

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence

VCAM-1/CD106 Monoclonal antibody specifically detects VCAM-1/CD106 in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.
Specifications

Specifications

VCAM-1/CD106
B-K9
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Purified
VCAM1
Activated human umbilical vein endothelial cells (HUVEC)
110 kDa
0.1 mg
Cancer, Mesenchymal Stem Cell Markers, Stem Cell Markers
Primary
7412
Human
Flow Cytometry, SDS-Page, Immunofluorescence
0.2 mg/mL
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 1 - 2 ug/ml
P19320
CD106, CD106 antigen, DKFZp779G2333, INCAM-100, L1CAM, MGC99561, vascular cell adhesion molecule 1, vascular cell adhesion protein 1, V-CAM 1, VCAM1, VCAM-1
Mouse
IgG1 Kappa
Protein A or G purified
RUO
Store at 4C.
Monoclonal
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
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