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Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Functional Grade, eBioscience™, Invitrogen™
Mouse Isotype Control
Supplier: Invitrogen 16471481
Description
Description: The monoclonal mouse IgG1 K immunoglobulin is useful as an isotype control. Applications Reported: This mouse IgG1 isotype control has been reported for use in surface and intracellular flow cytometric analysis, immunohistochemcial staining, immunoprecipitation and immunoblotting (WB). Applications Tested: This Mouse IgG1 isotype control has been tested by flow cytometric analysis of human peripheral leukocytes and can be used at the same concentration as the experimental antibody. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
Mouse IgG1 is a subtype of immunoglobulin G antibody that is produced by B cells in response to an antigen. It is the most abundant IgG subtype in the serum and plays a crucial role in the adaptive immune response. Mouse IgG1 is composed of two heavy chains and two light chains, and it is involved in opsonization, complement activation, and antibody-dependent cell-mediated cytotoxicity. It is also involved in the regulation of immune responses, including the activation of T cells and the inhibition of B cell activation. Mouse IgG1 is widely used in research and diagnostic applications, including ELISA, Western blotting, and immunohistochemistry. It is also used in therapeutic applications, such as immunotherapy and vaccine development.
Specifications
| Mouse IgG1 kappa | |
| P3.6.2.8.1 | |
| Functional Grade | |
| IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183 | |
| Affinity chromatography | |
| RUO | |
| Not Applicable | |
| Liquid |
| Control, Flow Cytometry, Functional Assay | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| Mouse | |
| 50 μg | |
| Isotype Control (Primary) | |
| 4° C | |
| IgG1 κ |
Safety and Handling
WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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