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Invitrogen™ Mouse IL-6 Platinum ELISA Kit Non-distribution product as customer accommodation.

Specifically engineered for accurate and precise measurement of IL-6 protein levels from samples including serum, plasma, and supernatants from cell cultures

Manufacturer:  Invitrogen™ BMS6032TWO

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Catalog No. 50-112-5447


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Includes: Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to mouse IL-6
Biotin-Conjugate anti-mouse IL-6 monoclonal antibody
Streptavidin-HRP
Mouse IL-6 Standard lyophilized, 4ng/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films

Description

Description

Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells. IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response. IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells. IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes. IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors. IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma. IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas. Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.
Specifications

Specifications

P08505
ELISA
Colorimetric Microplate Reader
ELISA Kit
RUO
Plasma,Serum,Supernatant
Plasma,50 μL|Serum,50 μL|Supernatant,50 μL
2-8°C
3 hr 30 min
Il6
8.9%
HRP
31.3-2,000 pg/mL
16193
Adhesive Plate Covers
2 x 96 tests
6.5 pg/mL
50μL
Mouse
1 hr 20 min
Mouse
Interferon-beta 2, B-cell stimulatory factor 2,HGF
5%
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