Invitrogen eBioscience Mouse IL-9 ELISA Ready-SET-Go! Kit, 2nd Generation
Specifically engineered for accurate and precise measurement of IL-9 protein levels from samples including serum, and cell culture supernatants. IL-9 is a 14 kd cytokine originally named P40 and identified by its proliferative effects on T cell population
Manufacturer: Invitrogen 88809277
DescriptionIL-9 is a 14 kDa cytokine originally named P40 and identified by its proliferative effects on T cell populations. The receptor, which is a heterodimer of the gamma chain portion of the IL-2 receptor and the IL-9R chain, activates Jak/STAT signaling pathways upon binding its ligand. Since the discovery of IL-9, numerous other functions have been observed. It induces Th17 and Treg differentiation in CD4+ T cells, IgE production in B cells, and the differentiation and proliferation of mast cells. IL-9 expression was initially observed in Th2 cells, but has since been found in Th17, eosinophil, and mast cells. Th9 cells, a newly discovered subset of CD4+ T cells, are characterized by the secretion of large amounts of IL-9 and IL-10. Th9 development is induced by stimulation of undifferentiated CD4+ with IL-4 and TGF beta. Th2 cells can also be driven towards a Th9 phenotype in the presence of TGF beta.
|96-well Plates: Corning Costar flat-bottom plates (included with Cat. Nos. ending in -22; -76; and -86)|
|20 x 96 tests|
|Serum,100 μL|Supernatant,100 μL|
|24 hr 30 min|
|Colorimetric Microplate Reader|
|1 hr 45 min|
|Interleukin-9, T-cell growth factor P40|
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