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Mouse SCF (aa 26-189), Recombinant Protein, Invitrogen™ Non-distribution product as customer accommodation.

E. coli Recombinant Protein

$225.00 - $1830.00

Specifications

Recombinant Yes
Name Mouse SCF (aa 26-189)
For Use With (Application) Control, ELISA, Western Blot
Concentration 200 µg/mL
Conjugate Unlabeled
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Products 4
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIRP87905 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87905
10 µg
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PIRP87906 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87906
25 µg
Each for $417.50
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PIRP87907 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87907
100 µg
Each for $931.00
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PIRP87908 Non-distribution product as customer accommodation.
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Thermo Scientific
RP87908
500 µg
Each for $1,830.00
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Description

Description

Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
Specifications

Specifications

Yes
Control, ELISA, Western Blot
Unlabeled
10 mM sodium phosphate with 150 mM NaCl and no preservative; pH 7.2
E. coli
-20°C
P20826
Kitl
>95%
Mouse SCF (aa 26-189)
200 µg/mL
Liquid
710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; mast cell growth factor; Mgf; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; SLF; Soluble KIT ligand; Steel factor; steel factor/kit ligand; stem cell factor; stem cell factor KL-1; stem cell factor, CSF
RUO
Mouse
17311
18 kD
SDS
Product Certifications
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