Potent inhibitor of microtubule formation (IC50 = 1.5 - 3.4nM); inhibits polymerization of tubulin in vitro and disrupts microtubule formation in several cancer cell lines. Inhibits tumor growth in vitro and in vivo; exhibits pro-apoptotic characteristics. Brain penetrant.
Chemical Name: N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinamine hydrochloride
CAS Number: 917369-31-4
Solubility: Soluble to 100mM in water and to 100mM in DMSO
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