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Tocris Bioscience™ MPEP hydrochloride

Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors

$196.67 - $796.67


Formula Weight Observed MW: 229.71
Molecular Formula C14H11N.HCl
Purity 99%
Target Group I mGluR Antagonists
Chemical Name or Material 2-Methyl-6-(phenylethynyl)pyridine hydrochloride
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Catalog Number Mfr. No. Quantity Price Quantity & Availability  
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Tocris Bioscience™
10 mg
Each for $196.67
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Tocris Bioscience™
50 mg
Each for $796.67
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Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.


Observed MW: 229.71
2-Methyl-6-(phenylethynyl)pyridine hydrochloride
Group I mGluR Antagonists
Soluble to 100mM in DMSO
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at +4°C

Product Certifications

For Research Use Only

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