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Tocris Bioscience™ MPEP hydrochloride
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
$220.40 - $890.88
Specifications
| Chemical Name or Material | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
|---|---|
| CAS | 219911-35-0 |
| Assay Percent Range | >99% |
| Solubility | Soluble to 100mM in DMSO |
| Target | Group I mGluR Antagonists |
Description
Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw.Specifications
| 2-Methyl-6-(phenylethynyl)pyridine hydrochloride | |
| >99% | |
| Group I mGluR Antagonists | |
| Observed MW: 229.71 |
| 219911-35-0 | |
| Soluble to 100mM in DMSO | |
| C14H11N.HCl | |
| 99% |
Safety and Handling
Recommended Storage : Desiccate at +4°C
For Research Use Only
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