DescriptionPotent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. Also available as part of the Group I mGlu Receptor Tocriset™ .
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|Observed MW: 229.71|
Safety and Handling
Recommended Storage : Desiccate at +4°C
For Research Use Only
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