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MPP8 Mouse anti-Human, Active Motif™ Non-distribution product as customer accommodation.

Mouse Recombinant Monoclonal Antibody

$98.40 - $465.85

Specifications

Monoclonal or Polyclonal Monoclonal
Primary or Secondary Primary
Antigen MPP8
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3798 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
91278
10 μg
Each for $98.40
Add to cart
 
50-199-3797 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
91277
100 μg
Each for $465.85
Add to cart
 
Description

Description

Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.
Specifications

Specifications

Monoclonal
Primary
MPP8
Unconjugated
SDS
Product Certifications
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