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MRC2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550956

Catalog No. PA550956


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Description

Description

MRC2 Polyclonal Antibody detects endogenous levels of MRC2 protein.

May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs). {ECO:0000269; PubMed:10683150, ECO:0000269; PubMed:12972549}.
Specifications

Specifications

MRC2
Polyclonal
Unconjugated
MRC2
Liquid
MRC2
Synthesized peptide derived from the N-terminal region of human Endo180.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q9UBG0, Q64449, Q4TU93
CLEC13E, ENDO180, KIAA0709, UPARAP
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
17534, 498011, 9902
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