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MRP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 195031AP

Catalog No. 50-173-2420


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Description

Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.
Specifications

Specifications

MRP5
0.46 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O15440, Q9QYM0, Q9R1X5
ABC33, ABCC5, MOAT C, MOATC, MRP5, pABC11, SMRP
Rabbit
IgG
150 μL
-20°C
Primary
10057, 116721, 27416
Immunohistochemistry (Paraffin)
Unconjugated
ABCC5
Liquid
Abcc5
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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