Invitrogen™ MRPL32 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109980

Catalog No. PIPA5109980

Description

Immunogen sequence: VLRNYWERLL RKLPQSRPGF PSPPWGPALA VQGPAMFTEP ANDTSGSKEN SSLLDSIFWM AAPKNRRTIE VNRCRRRNPQ KLIKVKNNID VCPECGHLKQ KHVLCAYCYE KVCKETAEIR RQIGKQEGGP FKAPTIETVV LYTGETPSEQ DQGKRIIERD RKRPSWFTQN.

Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-L32 (mitochondrial ribosomal protein L32), also known as HSPC283, is a 188 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 39S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. The gene encoding MRP-L32 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.

Specifications

• Antigen: MRPL32
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL32
• Gene Alias: 0610033O15Rik; 39S ribosomal protein L32, mitochondrial; bMRP-59b; Heart-expressed gene 1 protein; Heg1; HSPC283; L32mt; Mitochondrial large ribosomal subunit protein bL32m; mitochondrial ribosomal protein L32; MRPL32; MRP-L32
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64983, 75398
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.78 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BYC8, Q9DCI9
• Gene Symbols: MRPL32
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-188 of human MRPL32 (NP_114109.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG