Invitrogen™ MRPL35 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101361

Catalog No. PIPA5101361

Description

Antibody detects endogenous levels of total MRPL35.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants. Pseudogenes corresponding to this gene are found on chromosomes 6p, 10q, and Xp. [provided by RefSeq, Jul 2008].

Specifications

• Antigen: MRPL35
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL35
• Gene Alias: 1110066C01Rik; 39S ribosomal protein L35, mitochondrial; BM-007; L35mt; Mitochondrial large ribosomal subunit protein bL35m; mitochondrial ribosomal protein L35; MRPL35; MRP-L35; rm35
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51318, 66223
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9CQL6, Q9NZE8
• Gene Symbols: MRPL35
• Immunogen: A synthesized peptide derived from human MRPL35(Accession Q9NZE8), corresponding to amino acid residues V107-L157.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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