Invitrogen™ MRPL40 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5109982

Catalog No. PIPA5109982

Description

Immunogen sequence: MRSEPLRKKK KVDPKKDQEA KERLKRKIRK LEKATQELIP IEDFITPLKF LDKARERPQV ELTFEETERR ALLLKKWSLY KQQERKMERD TIRAMLEAQQ EALEELQLES PKLHAEAIKR DPNLFPFEKE GPHYTPPIPN YQPPEGRYND ITKVYTQVEF KR.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

Specifications

• Antigen: MRPL40
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL40
• Gene Alias: 39S ribosomal protein L40, mitochondrial; L40mt; Mitochondrial large ribosomal subunit protein mL40; mitochondrial ribosomal protein L40; MRPL22; MRP-L22; Mrpl40; MRP-L40; Nlvcf; nuclear localization signal protein absent in velo-cardio-facial patients; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; up-regulated in metastasis; URIM
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64976
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.7 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q9NQ50
• Gene Symbols: MRPL40
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 45-206 of human MRPL40 (NP_0037672).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG