Invitrogen™ MRPL43 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570588

Catalog No. PIPA570588

Description

This target displays homology in the following species: Cow: 79%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Rat: 83%.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.

Specifications

• Antigen: MRPL43
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL43
• Gene Alias: 39S ribosomal protein L43, mitochondrial; 4930442D21Rik; bMRP36a; L43mt; Mitochondrial large ribosomal subunit protein mL43; Mitochondrial ribosomal protein bMRP36a; mitochondrial ribosomal protein L43; MRPL43; MRP-L43; MRPL43 protein; putative; retina-specific 15.7 kDa protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 84545
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q8N983
• Gene Symbols: MRPL43
• Immunogen: synthetic peptide directed towards the middle region of human MRPL43 (aa 7-56).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG