MRPL45 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA589069

Catalog No. PIPA589069

Description

Immunogen sequence: MQHARKAGLV IPPEKSDRSI HLACTAGIFD AYVPPEGDAR ISSLSKEGLI ERTERMKKTM ASQVSIRRIK DYDANFKIKD FPEKAKDIFI EAHLCLNNSD HDRLHTLVTE HCFPDMTWDI KYKTVRWSFV ESLEPSHVVQ VRCSSMMNQG NVYGQITVRM HTRQTLAIYD RFGRLMYGQE DVPKDVLEYV VFEKQLTNPY GSWRMHTKIV PPWAPPKQPI LKTVMIPGPQ LKPEEEYEEA QGEAQKPQLA; Positive Samples: U-87MG, OVCAR3, 293T, Mouse brain, Mouse heart, Mouse kidney, Mouse liver, Mouse spleen, Rat brain; Cellular Location: Mitochondrion

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

Specifications

• Antigen: MRPL45
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPL45
• Gene Symbols: Mrpl45
• Immunogen: Recombit fusion protein containing a sequence corresponding to amino acids 57-306 of human MRPL45
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Concentration: 3.39 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BRJ2, Q9D0Q7
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 287656, 67036, 84311
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid