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MRPS12 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 152251AP

Catalog No. 50-173-0080


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Description

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal domit deafness gene (DFNA4). Splice variants that differ in the 5 ft. UTR have been found for this gene; all three variants encode the same protein.
Specifications

Specifications

MRPS12
0.24 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O15235, O35680
MPR S12, MRP S12, MRPS12, MT RPS12, RPMS12, RPS12, RPSM12, S12mt
Rabbit
IgG
150 μL
-20°C
Primary
24030, 292758, 6183
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
MRPS12
Liquid
MRPS12
MRPS12 Fusion Protein Ag7442
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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