Selective antagonist of P2Y6 nucleotide receptors; IC50 values are 37 and 98nM at human and rat P2Y6 receptors respectively. Displays no activity at P2Y1, P2Y2, P2Y4 and P2Y11 receptors (IC50 > 10µM). Inhibits agonist-induced cardiomyocyte contraction and UDP-induced phagocytosis.
Chemical Name: N,N''-1,4-Butanediylbis[N'-(3-isothiocyanatophenyl)thiourea
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