Tocris™ MRS 2578

Selective P2Y6 antagonist

Manufacturer: Tocris™ 2146/10

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Catalog No. 21-461-0R

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For Research Use Only


    Product Type MRS 2578
    Inhibitors MRS 2578
    Molecular Weight 472.66
    Quantity 10mg

    Selective antagonist of P2Y6 nucleotide receptors; IC50 values are 37 and 98nM at human and rat P2Y6 receptors respectively. Displays no activity at P2Y1, P2Y2, P2Y4 and P2Y11 receptors (IC50 > 10µM). Inhibits agonist-induced cardiomyocyte contraction and UDP-induced phagocytosis.

    • Chemical Name: N,N''-1,4-Butanediylbis[N'-(3-isothiocyanatophenyl)thiourea
    • Formula: C20H20N6S4
    • CAS Number: 711019-86-2
    • Solubility: Soluble to 50mM in DMSO

  • Description & Specifications

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