CD193 Rat anti-Mouse, Brilliant Violet 786, Clone: 83103, BD Optibuild
Rat Monoclonal Antibody
Manufacturer: BD Biosciences 740839
The 83103 monoclonal antibody specifically binds to CD193, which is also known as, C-C chemokine receptor type 3 (CCR3). CD193 is a chemokine receptor for CCL11/eotaxin, CCL24/eotaxin-2, CCL26/eotaxin-3, CCL5/RANTES, CCL7/MCP-3, CCL8/MCP-2, CCL14/MCP-4, CCL15/HCC-2 and CCL3/MIP-1a. CD193 is reportedly expressed on eosinophils, mast cells and Th2 cells. It plays an important role in eosinophil recruitment to the skin and the lung and in the development of airway hyperresponsiveness.
The antibody was conjugated to BD Horizon BV786 which is part of the BD Horizon Brilliant Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy7-like dyes (eg, 780/60-nm filter).
|Brilliant Violet 786|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|CCR3; CCR-3; chemokine (C-C) receptor 3; CC-CKR3; C-C CKR-3; CKR3; CC-CKR-3|
|Mouse CCR3 transfected Cells Transfected Cell Line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
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