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Tocris Bioscience™ MSC 2032964A

Potent and selective ASK1 inhibitor; orally bioavailable

Supplier:  Tocris Bioscience™ 5641/10

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Catalog No. 56-411-0


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Description

Description

MSC 2032964A is a potent and selective ASK1 inhibitor (IC50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant.
Specifications

Specifications

N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
10 mg
C16H13F3N6O
>98%
1124381-43-6
ASK1 Inhibitors
362.31
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Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

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