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Tocris Bioscience™ MSC 2032964A Available on GSA/VA Contract for Federal Government customers only.

Potent and selective ASK1 inhibitor; orally bioavailable

$213.50 - $847.00

Specifications

Chemical Name or Material N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
Molecular Formula C16H13F3N6O
CAS 1124381-43-6
Product Type Target: ASK1 Inhibitors
Formula Weight 362.31
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
56-411-0 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5641/10
10mg Each for $213.50
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56-415-0 View Documents Tocris Bioscience™
5641/50
50mg Each for $847.00
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Description

Description

Potent and selective ASK1 inhibitor (IC50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant.

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Specifications

Specifications

N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
1124381-43-6
362.31
C16H13F3N6O
Target: ASK1 Inhibitors
Safety and Handling

Safety and Handling

Recommended Storage : Store at −20°C

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