MSL1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 243731AP
DescriptionComponent of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at ft.Lys-16 ft. (H4K16ac) which is implicated in the formation of higher-order chromatin structure. Greatly enhances MSL2 E3 ubiquitin ligase activity, promoting monoubiquitination of histone H2B at ft.Lys-34 ft. (H2BK34Ub). This modification in turn stimulates histone H3 methylation at ft.Lys-4 ft. (H3K4me) and ft.Lys-79 ft. (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. In the MSL complex, acts as a scaffold to tether MSL3 and KAT8 together for enzymatic activity regulation.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|hMSL1, Male specific lethal 1 homolog, Male specific lethal 1 like 1, MSL 1, MSL1, MSL1 like 1, MSL1L1|
|MSL1 Fusion Protein Ag18024|
|Antigen Affinity Chromatography|
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