Invitrogen eBioscience Mouse TSLP ELISA Ready-SET-Go! Kit
Engineered for the accurate and precise measurement of mouse TSLP in serum, and tissue culture supernatant samples.
Manufacturer: Invitrogen 88749088
DescriptionTSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain. It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation. TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis. It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis. It is expressed in heart, liver and prostate.
|96-Well Plates: Corning Costar flat-bottom plates (included with Cat. Nos. ending in -22 and -86)|
|10 x 96 tests|
|Serum,100 μL|Supernatant,100 μL|
|24 hr 30 min|
|Colorimetric Microplate Reader|
|1 hr 45 min|
|Thymic Stromal-Derived Lymphopoietin|
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