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MT-ND3 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5120601

Encompass

Catalog No. PIPA5120601


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Description

Description

Positive test controls include: 293T, PC-3, Mouse heart, Mouse brain. Immunogen sequence: MNFALILMIN TLLALLLMII TFWLPQLNGY MEKSTPYECG FDPMSPARVP FSMKFFLVAI TFLLFDLEIA

NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MT-ND3
Polyclonal
Unconjugated
MT-ND3
1.6.5.3; mitochondrially encoded NADH dehydrogenase 3; Mtnd3; mt-Nd3; NADH dehydrogenase subunit 3; NADH3; NADH-ubiquinone oxidoreductase chain 3; ND3
Rabbit
Affinity Chromatography
RUO
17718, 26199, 4537
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
3.07 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
P03897, P03899, P05506
MT-ND3
A synthetic peptide corresponding to a sequence within amino acids 1-70 of human MT-ND3 (YP_0030240331)
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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