Invitrogen™ MTCH2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA525406

Catalog No. PIPA525406

Description

MTCH2 Polyclonal Antibody for Western Blot, IHC (P)

MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.

Specifications

• Antigen: MTCH2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mtch2
• Gene Alias: 2310034D24Rik; 4930539J07Rik; HSPC032; Met-induced mitochondrial protein; MIMP; mitochondrial carrier 2; mitochondrial carrier homolog 2; mitochondrial carrier homolog 2 (C. elegans); Mtch2; SLC25A50; solute carrier family 25, member 50
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 23788, 56428
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q791V5, Q9Y6C9
• Gene Symbols: Mtch2
• Immunogen: KLH conjugated synthetic peptide between 75-103 amino acids from the N-terminal region of human MTCH2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov